Preterm infants have significantly longer telomeres than their term born counterparts

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Preterm infants have significantly longer telomeres than their term born counterparts

There are well-established morbidities associated with preterm birth including respiratory, neurocognitive and developmental disorders. However several others have recently emerged that characterise an 'aged' phenotype in the preterm infant by term-equivalent age. These include hypertension, insulin resistance and altered body fat distribution. Evidence shows that these morbidities persist into...

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Infants born preterm exhibit different patterns of center-of-pressure movement than infants born at full term.

BACKGROUND Infants born preterm are at risk for developmental impairments related to postural control. OBJECTIVE The purpose of this study was to determine whether infants born preterm and infants born at full term differed in postural control at 1 to 3 weeks after term age. DESIGN This study included 17 infants born preterm (mean gestational age=31.9 weeks, range=25.0-34.6) and 15 infants ...

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Moderately preterm children have more respiratory problems during their first 5 years of life than children born full term.

RATIONALE Pulmonary outcomes of moderate-preterm children (MP) are unknown. OBJECTIVES To investigate the prevalence of respiratory symptoms during infancy and at preschool age of MP compared with full-term (FT) and early preterm children (EP) and to determine factors associated with respiratory symptoms of MP at school age. METHODS Prospective cohort study. OUTCOME VARIABLES number of re...

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Early and long-term outcome of infants born extremely preterm.

There is no question that birth at extremely low gestational ages presents a significant threat to an infant's survival, health and development. Growing evidence suggests that gestational age may be conceptualised as a continuum in which births before 28 weeks of gestation (extremely preterm: EP) represent the severe end of a spectrum of health and developmental adversity. Although comprising j...

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Preterm infants born at less than 31 weeks' gestation have improved growth in cycled light compared with continuous near darkness.

OBJECTIVES Our purpose was to evaluate the benefits of cycled light (CL) versus near darkness (ND) on health in preterm infants born at <31 weeks' gestational age. STUDY DESIGN Randomized, interventional study comparing infants receiving (1) CL from birth, (2) CL at 32 weeks' postconceptional age (PCA), and (3) CL at 36 weeks' PCA in transition for discharge home. Statistical significance was...

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ژورنال

عنوان ژورنال: PLOS ONE

سال: 2017

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0180082